Exploring the use of dogs as models for biological aging through methylation analysis.
- Dogs are being studied as potential models for biological aging, where researchers are exploring whether changes in epigenetic age are related to breed longevity.
- Differences in biological age among dogs of the same chronological age can be influenced by genetics, environment, behavior, and disease.
- The study investigates the feasibility of creating biological age methylation clocks in dogs, taking into account population stratification and breed standard metrics.
- Methylation-related markers reflecting biological age signals in dogs are rare and do not consistently appear across different datasets.
- The research aims to better understand the mechanisms of biological aging in dogs by analyzing methylation platforms and their signatures.
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Pathology & Lab Medicine, Aging, Methylation, Biological Aging, Domestic Dog