Study finds that Hydroxyurea has no negative impact on fertility for sickle cell disease patients

Study finds hydroxyurea has no impact on ovarian reserve in female sickle cell disease patients.

Hydroxyurea had no effect on ovarian reserve in female patients with sickle cell disease.
Sickle cell disease affects a significant number of individuals, particularly those of Black or African American descent.
Despite concerns about fertility, hydroxyurea has been shown to reduce vaso-occlusive crisis and hospitalization rates in patients with SCD.
Histological analysis revealed that hydroxyurea did not impact the quantity of primordial follicles in the ovaries of patients treated with the drug.
These findings suggest that fertility preservation measures may not be necessary for female patients with SCD undergoing hydroxyurea treatment.

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