Study reveals that daily routines are influenced by the number of receptors in the body's biological clock

Scientists at Washington University in St. Louis are uncovering how GABA receptors regulate circadian rhythms in the brain.

Signals from the central circadian clock in the brain generate seasonal and daily rhythms in humans and animals, helping the body prepare for environmental changes.
Researchers at Washington University in St. Louis studied how internal biological clocks keep time, answering questions about circadian rhythms.
The study focused on the role of GABA neurotransmitter in synchronizing circadian rhythms and found that receptor density impacts the amplitude of these rhythms.
Manipulating the density of GABA receptors in mice altered their circadian rhythms, affecting behavior and synchrony among SCN cells.
Understanding circadian rhythms is crucial as disruptions can lead to negative consequences such as fatigue, hormonal changes, gastrointestinal issues, and mood changes.

Study reveals that daily routines are influenced by the number of receptors in the body’s biological clock