Understanding the transmission of PVL-producing Staphylococcus aureus in families through pets.
- Panton-Valentine leucocidin (PVL)–producing Staphylococcus aureus (PVL-SA) is associated with skin and soft tissue infections, often transmitted through close contact.
- A family in Germany with recurrent PVL-SA infections underwent successful decolonization after multiple failed attempts.
- Cats in the household were identified as carriers of methicillin-susceptible S. aureus (MSSA), which contributed to the reinfections.
- Whole-genome sequencing revealed close clonal relationships between human and feline MSSA strains.
- Successful decolonization of both cats and the family was achieved through antimicrobial treatment and increased hygiene measures.
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Infectious Diseases, Family Medicine, Pediatrics