A recent study investigates the impact of testosterone therapy on breast tissue composition and breast cancer risk in trans masculine individuals.
- Lobular atrophy and stromal composition were assessed by pathologists in a study on testosterone therapy in breast tissue of trans masculine individuals.
- The duration of testosterone therapy was found to correlate with increasing degrees of lobular atrophy, but not with stromal composition.
- Research suggests that gender-affirming testosterone therapy may decrease the breast cancer risk for trans masculine individuals.
- Testosterone therapy was found to reduce the amount of breast epithelium in trans masculine individuals, potentially decreasing breast cancer risk.
- Further studies are needed to understand the interplay between testosterone therapy, obesity, and breast cancer risk in the trans masculine population.
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Endocrinology, Oncology, Transgender Health