New genetic and molecular risk factors for stroke recurrence identified, shedding light on potential treatments and preventive strategies.
- People who experience a stroke are at an increased risk of suffering a second stroke or other cardiovascular events, highlighting the importance of identifying risk factors and treatments to prevent recurrences.
- A recent study identified two proteins, CCL27 and TNFRSF14, associated with subsequent cardiovascular events but not initial strokes, suggesting inflammation plays a key role in stroke development.
- Utilizing genetic information from large biobanks, researchers conducted studies to find associations between DNA and stroke events, revealing potential novel drug targets for treating patients after their first stroke.
- The study found specific genetic variants that may be linked to subsequent major adverse cardiovascular events and subsequent ischemic strokes in certain populations, providing valuable insights into stroke progression.
- Identifying new drug targets for therapeutic interventions after a stroke could help prevent disabilities and mortality associated with stroke, particularly in populations disproportionately affected by strokes worldwide.
Source link
Neurology,Stroke,Research,Proteins,Recurrence