Summary
- A study of 8,737 patients with unstable angina found that 5.1% were readmitted for heart failure.
- Patients readmitted for heart failure were older, had atrial fibrillation, renal insufficiency, higher NT-proBNP levels, and poorer cardiac function.
- Higher levels of PM10 and CO were associated with an increased risk of heart failure readmission after discharge.
- PM10 and CO did not affect hospital mortality, initial heart failure, or stroke in unstable angina patients.
- Female patients with fewer underlying diseases were more sensitive to PM10 and CO exposure.
In a recent study involving patients with unstable angina, researchers found that certain air quality indicators may increase the risk of readmission for heart failure after discharge. The study included 8,737 patients, with 445 (5.1%) being readmitted due to heart failure and 8,292 (94.9%) not being readmitted.
Patients who were readmitted for heart failure after discharge were found to be older, with a higher prevalence of atrial fibrillation and renal insufficiency. They also had higher levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) and Troponin T (TNT), as well as poorer left ventricular ejection fraction. In terms of treatment, these patients were more likely to use spironolactone but less likely to use sodium-dependent glucose transporter 2 inhibitors.
The study also looked at the impact of air quality indicators on readmission for heart failure. It was found that higher levels of PM10 and CO were associated with an increased risk of heart failure readmission in patients with unstable angina. However, air quality indicators did not affect hospital mortality, initial heart failure, or stroke in these patients.
A decision tree model was constructed to further analyze how different levels of PM10 and CO affected the risk of heart failure readmission. The results showed that patients faced a higher risk of readmission when PM10 and CO levels exceeded certain thresholds. Patients with higher levels of PM10 and CO were at a greater risk of heart failure readmission.
Further analysis revealed that patients with certain characteristics, such as age, gender, BMI, and medical history, were more sensitive to PM10 and CO exposure. Female patients with fewer underlying diseases were found to be more sensitive to both PM10 and CO.
Overall, the study highlights the importance of considering air quality indicators in assessing the risk of readmission for heart failure in patients with unstable angina. By understanding the impact of air quality on patients’ health outcomes, healthcare providers can better tailor treatment and interventions to improve patient outcomes.
Cardiology,Pulmonary Medicine,Public Health & Prevention