Summary
- Neffy, a new epinephrine nasal spray, has been approved by the U.S. Food and Drug Administration for treating allergic reactions and anaphylaxis in adults and children over 66 pounds.
- Anaphylaxis is a severe allergic reaction that can be life-threatening and requires immediate treatment with epinephrine.
- Neffy was shown to have comparable effectiveness to epinephrine injections in studies, with similar increases in blood pressure and heart rate.
- Neffy is administered as a single dose nasal spray, although a second dose may be needed if symptoms do not improve or worsen.
- Common side effects of Neffy include throat irritation, headache, nasal discomfort, and tingling sensations.
The U.S. Food and Drug Administration has recently approved neffy (epinephrine nasal spray) as an emergency treatment for allergic reactions, specifically Type I reactions that can be life-threatening, such as anaphylaxis, in adults and children weighing at least 30 kilograms. This approval provides a non-injection option for individuals who may delay or avoid treatment due to fear of injections, making it easier for those in need to receive prompt medical attention. Anaphylaxis is a severe allergic reaction that can involve various parts of the body, requiring immediate treatment to prevent serious complications.
Neffy, a single-dose nasal spray, has been proven effective in studies comparing its performance to traditional injectable epinephrine products. This new treatment option has shown comparable blood concentration levels, as well as similar effects on blood pressure and heart rate, crucial factors in managing anaphylaxis. Patients experiencing anaphylactic episodes can administer neffy through the nostril, with the option of a second dose if needed. However, individuals with certain nasal conditions are advised to consult with healthcare professionals before using neffy, as absorption may be affected. The most common side effects of neffy include throat irritation, headache, and nasal discomfort, among others.
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Allergy & Clinical Immunology, Emergency Medicine, Pharmacists