- An international research team led by scientists from the Paul Langerhans Institute Dresden identified "first responder" cells in the pancreas that initiate the blood sugar response, crucial for managing diabetes.
- These first responder cells are more sensitive to glucose levels than other beta cells, acting as a control center for regulating the activity of the rest of the cells.
- Using zebrafish, researchers discovered that vitamin B6 production in the first responder cells is essential for the glucose response process in both fish and mouse pancreas.
- Vitamin B6 serves as a key enzyme involved in activating essential processes within cells, and its role in regulating glucose response could provide new insights into treating diabetes.
- Understanding how Vitamin B6 regulates beta cells in the pancreas may lead to new treatments for metabolic diseases like diabetes.
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Diabetes & Endocrinology, Immunology, Cell Biology, Endocrinology