Summary
- Patients undergoing maintenance hemodialysis were included in a study to assess the effects of oral nutritional supplementation.
- Patients were randomly assigned to receive a supplement during hemodialysis sessions or on non-dialysis days for 12 weeks.
- The primary outcome was the change in midweek predialysis serum albumin concentrations between the two groups.
- Secondary outcomes included changes in nutritional status, dietary intake, and body mass index.
- The study protocol adhered to ethical guidelines, and data analysis was conducted using statistical software to evaluate the results.
A recent study aimed to investigate the effects of oral nutritional supplementation during hemodialysis on patients with end-stage kidney disease (ESKD). The study included patients undergoing maintenance hemodialysis between September 2021 and March 2022. Patients had to meet specific criteria including being over 18 years old, receiving regular hemodialysis treatment for at least 6 months, and having adequate dialysis as indicated by certain measurements.
The study excluded patients with advanced liver disease, active malignancy, and other health issues that could interfere with the results. A total of 32 participants were involved in the research, with half receiving oral nutritional supplementation during hemodialysis sessions and the other half receiving it on non-dialysis days.
The primary outcome of the study was to assess changes in midweek predialysis serum albumin concentrations after 12 weeks of oral nutritional supplementation. Secondary outcomes included changes in the malnutrition inflammation score (MIS), dietary intake, and body mass index (BMI) between the two groups.
The Once Dialyze supplement provided to the patients contained proteins, carbohydrates, fats, electrolytes, and micronutrients. Patients were monitored throughout the study period, and various tests were conducted to evaluate their nutritional status, including blood tests and dietary recalls.
Ethical considerations were taken into account, and the study protocol received approval from the local Ethics Committee. Written informed consent was obtained from all participants, and the study adhered to the Declaration of Helsinki.
Statistical analysis was conducted to analyze the study results, with differences between groups assessed using various tests. The results were reported with a 95% confidence interval, and a P-value of 0.05 was considered statistically significant.
Overall, the study aimed to provide insights into the potential benefits of oral nutritional supplementation during hemodialysis for patients with ESKD. The findings could help improve the nutritional status and overall health outcomes of these patients.
In conclusion, the study highlighted the importance of adequate nutrition for patients undergoing hemodialysis and the potential benefits of oral nutritional supplementation in improving their health and well-being. Further research in this area could lead to more personalized care for patients with ESKD undergoing hemodialysis.
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Nephrology,Nutrition,Randomized Trial