Summary
- The study cohort was formed by linking data from the national hospital discharge registry HILMO and Finnish Cancer Registry (FCR), identifying inguinal hernia repairs and newly diagnosed prostate cancer cases in Finland.
- Information on diagnoses, procedures, and comorbid conditions were collected from the HILMO database, while information on prostate cancer cases was obtained from the FCR between 1998 and 2016.
- The study population included 7206 men diagnosed with localized prostate cancer managed primarily by prostatectomy or radiation therapy, with a focus on those with inguinal hernia operations before PCa management.
- Data linkage was possible due to the unique personal social security number assigned to all Finnish residents, allowing for the identification and analysis of the study population.
- Statistical analysis was conducted using SPSS, with a significance level set at p < 0.05, to analyze the relationship between inguinal hernia operations and prostate cancer management in Finnish men.
A study cohort was formed by linking data from the national hospital discharge registry HILMO and Finnish Cancer Registry. Information on inguinal hernia repairs among men in Finland from 1998 to 2016 was identified from the HILMO database. Common co-morbid conditions were also collected for analysis. The Finnish Cancer Registry provided information on newly diagnosed prostate cancer cases in Finland between 1998 and 2015. The study population was limited to 7206 men with prostate cancer managed primarily by prostatectomy or radiation therapy.
Data analysis was conducted using Statistical Package for Social Science for Windows, version 26.0 (SPSS). The study was carried out following good clinical practice and Declaration of Helsinki guidelines. Ethical approval was obtained from the National Research and Development Centre for Welfare and Health, and informed consent was waived as the study used routinely collected registry data. The study was conducted in compliance with Finnish legislation, and the local ethics committee did not require any further actions to be taken.
Overall, the study aimed to investigate the association between inguinal hernia repair and prostate cancer management outcomes in Finnish men. The researchers were able to link information from different registries due to the unique personal social security number given to all Finnish residents. The findings of the study are important for understanding potential impacts of inguinal hernia repair on prostate cancer outcomes.
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General Surgery,Urology