Risk Factors for Severe COVID-19
- Genetic factors play a crucial role in determining the severity of COVID-19 in individuals.
- Researchers from the University of Bonn investigated a large group of individuals and identified the TLR7 gene as a key player in severe cases of the disease.
- In addition to TLR7, mutations in three other genes of the immune system were also found to contribute to severe COVID-19.
- The study revealed that genetic changes in TLR7 were more frequently observed in women with severe COVID-19 courses, indicating gender-specific differences in disease progression.
- Understanding these genetic factors can help identify at-risk individuals, develop targeted therapies, and prepare for future pandemics.
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Infectious Diseases,Pulmonary Medicine,Genetics