Study shows traffic-related ultrafine particles impair mitochondrial functions in human olfactory mucosa cells, shedding light on Alzheimer’s disease risks.
- Ultrafine particles (UFPs), the smallest contributors to air pollution, impair mitochondrial functions in human olfactory mucosa cells.
- Research led by the University of Eastern Finland found that traffic-related UFPs affect oxidative phosphorylation and redox balance in cells.
- Individuals with Alzheimer’s disease (AD) showed different responses in olfactory mucosa cells compared to healthy controls.
- Air pollution, including UFPs, is a significant risk factor for dementia, such as AD, but its specific role in brain changes remains unclear.
- The study highlights the importance of understanding the impact of air pollutants on human health, particularly individuals with AD, to guide preventive measures and reduce health burdens.
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Otolaryngology,Oncology,Public Health & Prevention