Study reveals oligodendrocytes’ role in Alzheimer’s disease by producing toxic protein, providing new insights for potential treatments.
- Oligodendrocytes produce amyloid beta (Aβ) protein implicated in causing Alzheimer’s disease
- Study shows key role of oligodendrocyte-derived Aβ in promoting neuronal dysfunction in AD
- Suppressing Aβ production in oligodendrocytes can rescue abnormal neuronal hyperactivity in AD mouse model
- Targeting oligodendrocyte Aβ production could be a promising therapeutic strategy for treating AD
- Results challenge the belief that neurons are the exclusive source of Aβ and suggest a new approach in Alzheimer’s disease treatment.
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Neurology, Alzheimer’s disease, Oligodendrocytes