Study reveals the impact of children’s exposome on serum metabolites associated with cardiometabolic health.
- A study from the University of Eastern Finland suggests that a combination of environmental exposures and unhealthy lifestyle habits can impact children’s cardiometabolic health more significantly than each factor alone.
- An exposome score measuring multiple environmental and lifestyle factors was associated with changes in serum metabolites related to cardiometabolic health in children aged 6-9 years old.
- The study, part of the LongITools project, involved 504 children followed up for eight years in the PANIC Study in Finland, showing the importance of assessing the combined effect of various exposures.
- Some serum metabolites linked to an unhealthy exposome score, such as phospholipids and amino acids, have been associated with conditions like obesity, type 2 diabetes, and cardiovascular diseases later in life.
- The associations between the exposome score and serum metabolites were influenced by adiposity levels, indicating a potential impact of body fat content on metabolic changes associated with adverse exposures.
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Pediatrics, Public Health & Prevention, Pediatrics