Researchers have developed a novel 3D cell culture platform to improve drug testing for esophageal cancer, enhancing chemotherapy effectiveness.
- Researchers have developed a microfluidic chip-based approach to assess and screen esophageal cancer drugs using a three-dimensional scaffold to mimic the in vivo tumor environment.
- Esophageal cancer is a common and deadly form of cancer, with limited treatment options beyond surgery and chemotherapy.
- Conventional drug development for esophageal cancer has been hindered by using two-dimensional cell culture models that do not accurately represent the physiological conditions of cancer cells.
- The new microfluidic chip enables the screening of chemotherapy drugs on 3D tumor spheroids, providing a more accurate representation of cellular response and intracellular factors.
- The innovative technology has the potential to advance drug development for esophageal cancer and other diseases, paving the way for personalized medicine applications.
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Oncology, Pharmacists, Pathology & Lab Medicine