- A UNIGE team studied patients with a genetic anomaly linked to psychotic disorders to identify predictive markers for psychosis.
- The study focused on individuals with the 22q11.2DS microdeletion, which can lead to psychotic disorders in adolescence or adulthood.
- Researchers found that individuals with the microdeletion had unique brain interconnections, with some areas displaying over- or under-coupling.
- The study showed that individuals with the microdeletion had developmental discrepancies in brain regions responsible for functions like voluntary motor coordination and decision-making.
- This research paves the way for identifying reliable risk markers for psychosis and could lead to personalized assessments of an individual’s risk of developing the disorder.
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Neurology, Psychiatry & Mental Health