Crimean-Congo hemorrhagic fever (CCHF) is an emerging disease, with testing saliva and urine for diagnosis showing promising results.
- Crimean-Congo hemorrhagic fever (CCHF) is caused by CCHV virus and is listed as a priority pathogen by the World Health Organization.
- A study in Iran analyzed the utility of saliva and urine samples for laboratory diagnosis of CCHF using real-time reverse transcription PCR.
- The study found that serum provided the most suitable sample type for identifying CCHFV RNA, with highest positivity rates in serum compared to saliva and urine samples.
- CCHFV RNA was detected in all sample types but with different rates and time frames, providing a wider diagnostic window with serum samples.
- The study also found that CCHFV antigen had lower positivity rates in serum and saliva samples compared to RNA testing, and IgM was detectable in serum samples from the second day of the disease onwards.
Source link
Infectious Diseases, Public Health & Prevention