- Recent study published in Nature tracked brain changes in healthy adults before, during, and after high-dose psilocybin administration
- Psilocybin caused significant disruptions in brain connectivity, especially in the default mode network, lasting for weeks
- Psilocybin desynchronizes brain networks and induces lasting neuroplastic changes linked to therapeutic effects
- Study compared psilocybin with a control drug, methylphenidate, and found psilocybin’s effects to be over three times larger
- Psilocybin’s impact on brain desynchronization can be mitigated by task engagement, suggesting potential for therapeutic applications.
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Neurology, Psychiatry & Mental Health, Pharmacists, Public Health & Prevention