Experts are looking into a fresh strategy for testing vaccines and getting ready for pandemics.

An international consortium of experts innovates vaccine trials for future pandemics with adaptive platform trials.

A white paper by an international consortium led by Professor Oliver A. Cornely explores innovative approaches for clinical vaccine research to better prepare for future pandemics.
The paper introduces adaptive platform trials (APTs) as a new type of clinical trial that allows for flexible study design adjustments during the trial.
Mathematical-statistical modeling and artificial intelligence are utilized to optimize data collection and decision-making in APTs for vaccine research.
A study infrastructure is crucial for the success of APTs, enabling rapid response to emergencies and the ability to address neglected research areas outside of pandemics.
The VACCELERATE consortium has established structures like the Volunteer Registry and Site Network to support the development and implementation of vaccine APTs for pandemic preparedness.

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