New research explores a new technique, burst sine wave electroporation (B-SWE), to tackle aggressive brain tumors with improved blood-brain barrier disruption.
- Researchers have developed a new technique called burst sine wave electroporation (B-SWE) to target glioblastoma, a deadly brain tumor.
- B-SWE disrupts the blood-brain barrier around the tumor site while causing minimal damage to healthy tissue.
- The study found that B-SWE results in better blood-brain barrier disruption compared to conventional square waveforms used in high frequency irreversible electroporation (H-FIRE).
- B-SWE could potentially allow more cancer-fighting drugs to access the brain by disrupting the blood-brain barrier.
- Further research is needed to study the effects of B-SWE on brain cancer in animal models to compare its efficacy to the conventional H-FIRE technique.
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Neurology,Oncology,Public Health & Prevention