Study finds significant gaps in genetic screening for hereditary cancer syndromes, especially among underrepresented minorities.
- Current screening protocols are inadequate in identifying individuals with genetic mutations linked to hereditary breast and ovarian cancer syndrome and Lynch syndrome, especially among underrepresented minorities.
- A study by Mayo Clinic Center for Individualized Medicine identified 550 carriers of hereditary mutations out of over 44,000 participants, with half being unaware of their genetic risk.
- Mutations in BRCA1 and BRCA2 genes increase the risk of breast, ovarian, prostate, and pancreatic cancers, while Lynch syndrome is associated with colorectal and uterine/endometrial cancers.
- Disparities exist in how underrepresented minorities meet genetic testing guidelines, leading to disparities in cancer prevention and care.
- The Tapestry project aims to advance personalized medicine by integrating genetic information into electronic health records, paving the way for targeted health interventions for all individuals.
Source link
Oncology, Genetics, Cancer Risk