Explore the zonal origins of BPH and prostate cancer in a systematic review published by Xia & He Publishing Inc.
- Benign prostatic hyperplasia (BPH) and prostate cancer (PCa) are common prostate conditions among elderly men, with PCa being the most prevalent non-skin cancer in the United States.
- Recent studies suggest an inverse relationship between prostate size due to BPH and the incidence of PCa, with a larger prostate size potentially being protective against PCa.
- A systematic review published in Exploratory Research and Hypothesis in Medicine aims to provide an overview of the zonal origins of BPH and PCa within the prostate.
- The review included thirty-eight studies showing that BPH primarily develops in the transition zone (TZ) and PCa in the peripheral zone (PZ) of the prostate.
- The findings highlight the importance of understanding the dynamic interactions between different prostate zones and the potential impact of BPH size on PCa development.
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Urology, Oncology, Pathology & Lab Medicine